Levi Yant

Current

• PhD Student at Max Planck Institute

Past

• PhD Student at University of Wisconsin
• Researcher at University of Wisconsin

Education

• Eberhard-Karls-Universität Tübingen
• University of Wisconsin-Madison
• University of Toronto

• Beloit College

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Connections

16 connections

Industry

Research

Websites

• My research website

Levi Yant’s Summary

How are complex organs formed? Plants provide an incredible system to better understand this and many of the most fundamental questions in development.

I'm working on untangling a major developmental transition in angiosperms, the reproductive transition to flowering. By using full genome scale ChIP-chip, ChIP-seq, and other microarray platforms, I'm discovering the direct targets of the transcription factors that govern this transition.

Levi Yant’s Specialties:

massively parallel next generation genome sequencing (Illumina), various microarray technologies, various molecular virology, cellular immunology, and molecular biology techniques, QPCR expression analysis, chromatin immunoprecipitation, management skills, road and mountain biking, and rock climbing

Levi Yant’s Experience

• PhD Student

  Max Planck Institute

  (Research industry)

  October 2006 — Present (3 years 3 months)

  I'm really interested in the genetic regulatory networks that control major developmental transitions and how they are recruited differently over evolutionary time.
  Right now, I'm employing novel genome-scale approaches (ChIP-Seq, ChIP-chip, other microarray platforms) to disentangle the gene regulatory network governing in the reproductive transition to flowering. I'm approaching this network both from the perspective of direct repressors and promoters in particular genetic nodes to gain a better understanding of the structure of a complex, yet tractable, gene network.
  
  Aside from science, I love to ride my bike obsessively, climb, and read.
  
  1. Yant L, Mathieu J, Schmid M. Just Say "no"; floral repressors help Arabidopsis bide the time. Current Opinion in Plant Biology. Epub 2009 Aug 18.
  
  2. Bomblies K, Yant L, Laitinen R, Kim ST, Weigel D. A high-resolution study of local population dynamics in Arabidopsis thaliana. in review.
  
  3. Salomé PA, Bomblies K, Laitinen R, Yant L, Warthmann N, Weigel D. Recombinational landscape of Arabidopsis thaliana populations after a single meiosis. in review.
  
  4. Mathieu J, Yant LJ, Mürdter F, Küttner F, Schmid M. Repression of flowering by the miR172 target SMZ. PLoS Biology, Jul;7(7):e1000148. Epub 2009 Jul 7.

• PhD Student

  University of Wisconsin

  (Educational Institution; 10,001 or more employees; Higher Education industry)

  August 2003 — October 2006 (3 years 3 months)

  Discovery of associations of MHC class I alleles with reduced AIDS virus replication in vivo, and detailed immunologic characterizations
  
  
  Selected papers (of 5):
  Yant LJ, Friedrich TC, Johnson RC, May G, Maness NJ, Lifson J, O’Connor DH, Carrington M, Watkins DI. The High Frequency MHC Class I Allele Mamu-B*17 is Associated with Control of SIVmac239 Replication J.Virol 2006; 80(10)
  
  Wojcechowskyj JA,.Yant LJ,.Wiseman RW, and O’Connor DH. Control of SIVmac239 is not predicted by inheritance of Mamu-B*17-containing haplotypes. J.Virol. 2007; 81
  
  Maness NJ, Yant LJ, Chung C, Friedrich TC, May GE, Soma T, Leon EJ, Wilson NA, Piontkivska H, Hughes AL, Sidney J, Sette A, Watkins DI. Comprehensive immunological evaluation of elite controller and progressor Mamu-B*17-positive SIV-infected rhesus macaques reveals surprisingly few differences. J Virol in press
  
  Patent:
  “Novel Approach to Broaden and Strengthen Cellular Immune Responses for a Global AIDS Vaccine"

• Researcher

  University of Wisconsin

  (Educational Institution; 10,001 or more employees; Higher Education industry)

  2001 — 2004 (3 years )

  Selected papers (of 7)
  Yant LJ, Ran Q, Rao L, Van Remmen H, Shibatani T, Belter JG, Motta L, Richardson A, Prolla TA. The selenopotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults. Free Radic Biol Med. 2003 Feb 15;34(4):496-502
  
  Friedrich TC, Dodds E, Yant LJ, Rudersdorf R, Cullen C, Evans ET, Desrosiers RC, Mothé BR, Sidney J, Sette A, Kunstman K, Wolinsky S, Piatak M, Lifson J, Wilson N, O’Connor DH, Watkins DI. Reversion of cytotoxic T-lymphocyte (CTL) escape variant immunodeficiency viruses in vivo. Nature Medicine 2004 Mar;10(3):275-81.
  
  Friedrich TC, Frye CA, Yant LJ, O’Connor DH, Kriewaldt N, Benson M, Dodds EJ, Cullen C, Rudersdorf R, Hughes AL, Wilson N, Watkins DI. Extra-epitopic compensatory substitutions restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic T-lymphocyte response. J.Virol 2004 Mar;78(5):2581-5.

Levi Yant’s Education

• Eberhard-Karls-Universität Tübingen

  PhD , Developmental Genetics , 2006 — 2009

• University of Wisconsin-Madison

  Master of Science , Pathology , 2004 — 2006

• University of Toronto

  Master of Arts , History of Philosophy , 2001 — 2004

• Beloit College

  Bachelor of Arts , Classics, Biochemistry , 1996 — 2000

  Activities and Societies:

  Classics, cross country, track, an excessive obsession with playing the cello

Additional Information

Levi Yant’s Websites:

• My research website

Levi Yant’s Interests:

Climbing and cycling.

Levi Yant’s Honors:

magna cum laude, various fellowships, that whole shtick.

Levi Yant’s Contact Settings

Interested In:

• new ventures
• job inquiries
• getting back in touch